Stimuli-Responsive, Plasmonic Nanogel for Dual Delivery of

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Herein the state of the art of stimuli‐responsive polymeric nanoparticles are reviewed. Such systems are able to control drug release by reacting to naturally occurring or external applied stimuli. Special attention is paid to the design and nanoparticle formulation of these so‐called smart drug‐delivery systems. Dual stimuli‐responsive nanoparticles capable of fine‐tuning drug release to augment therapeutic efficacy have become a promising tool for anticancer drug delivery. However, the rational design of these “smart” nanoparticles for a selective delivery and controlled release of multidrug combinations in cancer cells to achieve synergistic effects remain challenging.

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy A principal goal of cancer nanomedicine is to deliver therapeutics effectively to cancer cells within solid tumors. However, there are a series of biological barriers that impede nanomedicine from reaching target cells. Herein the state of the art of stimuli‐responsive polymeric nanoparticles are reviewed. Such systems are able to control drug release by reacting to naturally occurring or external applied stimuli. Special attention is paid to the design and nanoparticle formulation of these so‐called smart drug‐delivery systems. Dual stimuli‐responsive nanoparticles capable of fine‐tuning drug release to augment therapeutic efficacy have become a promising tool for anticancer drug delivery. However, the rational design of these “smart” nanoparticles for a selective delivery and controlled release of multidrug combinations in cancer cells to achieve synergistic effects remain challenging.

size, zeta potential, and drug release rate) in accordance with the endogenous stimuli of the tumor microenvironment made possible the ultimate overcoming of these barriers, especially the bottleneck of tumor penetration. The STIRENA project focused on the development of novel stimuli-responsive nanoparticles for potential applications as drug delivery By integrating inorganic NPs such as gold NPs, quantum dots, and iron oxide nanoparticles with fDNA, we designed stimuli-responsive fDNA–NPs that exhibit target induced assembly and disassembly of NPs, resulting in a variety of colorimetric, fluorescent, and magnetic resonance imaging (MRI)-based sensors for diagnostic of a broad range of analytes.

MTD2017 Västerås abstracts - Svensk Medicinteknisk Förening

density gradient centrifugation applied on commercial gold nanoparticles example the formation of stimuli-responsive colloidal gels and colloidosomes [1]. 2689 dagar, Oral delivery of proteins by biodegradable nanoparticles. 2689 dagar, Reversal of multidrug resistance by stimuli-responsive drug delivery systems •Magnetic Nanoparticles. References / Latest synthesis of functional nanoparticles Fine-Tuning the Structure of Stimuli-Responsive Polymer Films by.

MONODISPERSE - Uppsatser.se

2016-12-12 2016-03-24 Nanoparticles, in situ, self-assembled nanoparticles, nanoprecipitation, stimuli-responsive drug release.

3 (Mar 08 nanofabrication; localized surface plasmon resonance; alloy nanoparticles; of optical and electrical pH sensors based on stimuli-responsive hydrogels. Disease via pH-Responsive BabA-Mediated Adherence.
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2018-02-13 2019-01-10 Adapted with permission from ref. 30 (copyright 2015, American Chemical Society). (e) Reversible self-assembly of NPs controlled by a photoacid. Adapted with permission from ref. 31 (copyright 2015, Nature Publishing Group).

These nanoparticles either response to internal Recent advances in synthesis and fabrication of stimuli-responsive polymeric nanoparticles with built-in stimuli-responsive components (Part A) and surface Stimuli-responsive nanoparticles as emerging controlled drug release systems.
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Temperature and pH Controlled Self-Assembly of a Protein

1095-1112. Apr 12, 2016 We developed a stimuli-responsive clustered nanoparticle (iCluster) and justified that its adaptive alterations of physicochemical properties (e.g. May 12, 2017 There is increasing evidence that stimuli‐responsive nanomaterials have become significantly critical components of modern materials design stimuli-responsive delivery of therapeutics and contrast agents into a diseased cell.

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Disputation: Magnetically governed self-assembly of soft

It confers several merits over conventional formulations like increased solubility and bioavailability, targeted drug delivery and a decreased dose of the 2019-09-21 Against this backdrop, stimuli-responsive antibiotic-loaded nanoparticles and materials with antimicrobial properties (nanoantibiotics) present the ability to enhance therapeutic efficacy, while also reducing drug resistance and side effects.